Key features and details
- Rabbit monoclonal [NO.H1B0] to MERTK
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MERTK antibody [NO.H1B0]
See all MERTK primary antibodies
DescriptionRabbit monoclonal [NO.H1B0] to MERTK
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
- WB: HEK-293T cell extract. IHC-P: Human tonsil tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
Our Abpromise guarantee covers the use of ab238516 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 110 kDa.|
|IHC-P||1/50 - 1/200.|
FunctionIn case of filovirus infection, seems to function as a cell entry factor.
Tissue specificityNot expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines.
Involvement in diseaseDefects in MERTK are the cause of retinitis pigmentosa type 38 (RP38) [MIM:613862]. RP38 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
- Information by UniProt
- c MER antibody
- c mer proto oncogene tyrosine kinase antibody
- c-mer antibody
Anti-MERTK antibody [NO.H1B0] (ab238516) at 1/500 dilution + HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell extract at 25 µg
HRP Goat Anti-Rabbit IgG (H+L) at 1/10000 dilution
Predicted band size: 110 kDa
Paraffin-embedded human tonsil tissue stained for MERTK using ab238516 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab238516 has not yet been referenced specifically in any publications.