Mesalamine, anti-inflammatory agent (ab143052)

Overview

  • Product name

    Mesalamine, anti-inflammatory agent
  • Description

    Anti-inflammatory compound
  • Biological description

    Anti-inflammatory compound. Requires bioactivation by cytochrome P450 in vitro and in vivo.
  • Purity

    > 99%
  • CAS Number

    89-57-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-Amino-2-hydroxybenzoic acid
  • Molecular weight

    153.14
  • Molecular formula

    C7H7NO3
  • PubChem identifier

    4075
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1M HCl to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=C(C=C1N)C(=O)O)O
  • Source

    Synthetic

References

This product has been referenced in:

  • Huttunen KM  et al. Design, synthesis, and evaluation of novel cyclic phosphates of 5-aminosalicylic acid as cytochrome p450-activated prodrugs. Mol Pharm 10:532-7 (2013). Read more (PubMed: 22937971) »
  • Khare V  et al. Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1. Biochem Pharmacol 85:234-44 (2013). Read more (PubMed: 23146664) »

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