Overview

  • Product name

    Anti-Mesothelioma antibody [HBME-1]
    See all Mesothelioma primary antibodies
  • Description

    Mouse monoclonal [HBME-1] to Mesothelioma
  • Host species

    Mouse
  • Specificity

    This antibody reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesothelimias in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.
  • Tested applications

    Suitable for: IHC-P, IHC-Frmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Suspension of human mesothelioma cells from patients with malignant epithelial mesothelioma.

  • Positive control

    • Mesothelioma.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituent: 1% BSA
  • Concentration information loading...
  • Purity

    Purified IgM
  • Clonality

    Monoclonal
  • Clone number

    HBME-1
  • Myeloma

    unknown
  • Isotype

    IgM
  • Light chain type

    unknown
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notes
    IHC: This antibody may be diluted to a titer of 1:12-1:25 in an ABC method.
    We suggest an incubation period of 60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
    Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
  • Target

    • Relevance

      Mesothelioma is a rare form of carcinoma of the mesothelial cells which that normally line the body cavities, including the pleura, peritoneum, pericardium, and testis. It may be localized or diffuse. Most, but not all, cases of pleural malignant mesothelioma are associated with asbestos exposure.
    • Alternative names

      • Malignant mesothelioma susceptibility to antibody
      • MMS antibody

    Images

    • ab2383 staining human mesothelioma by IHC-P.
    • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human mesothelioma tissue, staining Mesothelioma with ab2383.

    References

    This product has been referenced in:

    • Chernova T  et al. Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). Curr Biol 27:3302-3314.e6 (2017). Read more (PubMed: 29112861) »
    See 1 Publication for this product

    Customer reviews and Q&As

    Question
    Answer

    Thank you for contacting Abcam regarding ab2383.


    The average concentration of this antibody is 45mg/L. If you have a specific lot number, I can check for that concentration as well.


    I hope this information is helpful. Please do not hesitate to contact us if you have any additional questions.

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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