Validated using a knockout cell line

Recombinant Anti-Met (c-Met) antibody [EP1454Y] - N-terminal (ab51067)

Knockout Tested Rabbit recombinant monoclonal Met (c-Met) antibody [EP1454Y]. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human. Cited in 40 publication(s).

Publishing research using ab51067? Please let us know so that we can cite the reference in this datasheet.

ab51067 has been referenced in 47 publications.

  • Kuo CS  et al. Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP-10 and MET. Allergy N/A:N/A (2019). PubMed: 30667542
  • Cheng Y  et al. Correlation the between the regulation of miRNA-1 in c-Met-induced EMT and cervical cancer progression. Oncol Lett 17:3341-3349 (2019). PubMed: 30867768
  • Nakayama I  et al. Enrichment of CLDN18-ARHGAP fusion gene in gastric cancers in young adults. Cancer Sci 110:1352-1363 (2019). PubMed: 30771244
  • Yu J  et al. LncRNA CCAT1 negatively regulates miR-181a-5p to promote endometrial carcinoma cell proliferation and migration. Exp Ther Med 17:4259-4266 (2019). PubMed: 30988798
  • Bastounis EE  et al. Matrix stiffness modulates infection of endothelial cells by Listeria monocytogenes via expression of cell surface vimentin. Mol Biol Cell 29:1571-1589 (2018). PubMed: 29718765
  • Du S  et al. NADPH oxidase 4 regulates anoikis resistance of gastric cancer cells through the generation of reactive oxygen species and the induction of EGFR. Cell Death Dis 9:948 (2018). PubMed: 30237423
  • Zhang M  et al. A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma. Nat Commun 9:4475 (2018). PubMed: 30367041
  • Owen GI  et al. Chilean Gastric Cancer Task Force: A study protocol to obtain a clinical and molecular classification of a cohort of gastric cancer patients. Medicine (Baltimore) 97:e0419 (2018). PubMed: 29668600
  • Chen C  et al. PF-2341066 combined with celecoxib promotes apoptosis and inhibits proliferation in human cholangiocarcinoma QBC939 cells. Exp Ther Med 15:4543-4549 (2018). PubMed: 29725387
  • Yang YN  et al. miR-204 reverses temozolomide resistance and inhibits cancer initiating cells phenotypes by degrading FAP-a in glioblastoma. Oncol Lett 15:7563-7570 (2018). PubMed: 29725461
  • Heublein S  et al. Association of differential miRNA expression with hepatic vs. peritoneal metastatic spread in colorectal cancer. BMC Cancer 18:201 (2018). IHC . PubMed: 29463215
  • Wang QY  et al. MiR-133b targets Sox9 to control pathogenesis and metastasis of breast cancer. Cell Death Dis 9:752 (2018). PubMed: 29970901
  • Odenthal J  et al. Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma. Sci Rep 8:10467 (2018). PubMed: 29992954
  • Huang X  et al. Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis. Oncol Lett 15:947-955 (2018). PubMed: 29422968
  • Dong G  et al. MACC1 and HGF are associated with survival in patients with gastric cancer. Oncol Lett 15:3207-3213 (2018). PubMed: 29435059
  • Gong XY  et al. Prognostic significance of c-Met, ß-catenin and FAK in patients with hepatocellular carcinoma following surgery. Oncol Lett 15:3796-3805 (2018). PubMed: 29467897
  • Han Z  et al. Development of a SPECT Tracer to Image c-Met Expression in a Xenograft Model of Non-Small Cell Lung Cancer. J Nucl Med 59:1686-1691 (2018). PubMed: 29777004
  • Gu X  et al. rHGF interacts with rIGF-1 to activate the satellite cells in the striated urethral sphincter in rats: a promising treatment for urinary incontinence? Arch Gynecol Obstet 298:1149-1157 (2018). PubMed: 30306312
  • Liu H  et al. LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling. J Exp Clin Cancer Res 37:279 (2018). PubMed: 30463570
  • El-Habta R  et al. The adipose tissue stromal vascular fraction secretome enhances the proliferation but inhibits the differentiation of myoblasts. Stem Cell Res Ther 9:352 (2018). PubMed: 30572954
  • Steele AN  et al. A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. Biotechnol Bioeng 114:2379-2389 (2017). PubMed: 28574594
  • Jahangiri A  et al. Cross-activating c-Met/ß1 integrin complex drives metastasis and invasive resistance in cancer. Proc Natl Acad Sci U S A 114:E8685-E8694 (2017). PubMed: 28973887
  • Pool M  et al. 89Zr-Onartuzumab PET imaging of c-MET receptor dynamics. Eur J Nucl Med Mol Imaging 44:1328-1336 (2017). PubMed: 28315949
  • Price EW  et al. 89Zr-DFO-AMG102 Immuno-PET to Determine Local Hepatocyte Growth Factor Protein Levels in Tumors for Enhanced Patient Selection. J Nucl Med 58:1386-1394 (2017). PubMed: 28280216
  • Cho SH  et al. The Antitumor Effect of C-terminus of Hsp70-Interacting Protein via Degradation of c-Met in Small Cell Lung Cancer. Korean J Thorac Cardiovasc Surg 50:153-162 (2017). PubMed: 28593150
  • Wang H  et al. Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways. BMC Cancer 17:191 (2017). PubMed: 28292264
  • Wang H  et al. DCLK1 is correlated with MET and ERK5 expression, and associated with prognosis in malignant pleural mesothelioma. Int J Oncol 51:91-103 (2017). PubMed: 28560410
  • Xie C  et al. Expression of c-Met and hepatocyte growth factor in various gastric pathologies and its association withHelicobacter pyloriinfection. Oncol Lett 14:6151-6155 (2017). PubMed: 29113260
  • Iseki M  et al. Muse Cells, Nontumorigenic Pluripotent-Like Stem Cells, Have Liver Regeneration Capacity Through Specific Homing and Cell Replacement in a Mouse Model of Liver Fibrosis. Cell Transplant 26:821-840 (2017). PubMed: 27938474
  • Jia Y  et al. c-MET inhibition enhances the response of the colorectal cancer cells to irradiation in vitro and in vivo. Oncol Lett 11:2879-2885 (2016). WB ; Human . PubMed: 27073569
  • Kobayashi K  et al. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep 5:8428 (2015). IHC . PubMed: 25673149
  • Wu H  et al. Norcantharidin combined with EGFR-TKIs overcomes HGF-induced resistance to EGFR-TKIs in EGFR mutant lung cancer cells via inhibition of Met/PI3k/Akt pathway. Cancer Chemother Pharmacol 76:307-15 (2015). PubMed: 26063323
  • Matsumoto Y  et al. A phase II study of erlotinib monotherapy in pre-treated non-small cell lung cancer without EGFR gene mutation who have never/light smoking history: re-evaluation of EGFR gene status (NEJ006/TCOG0903). Lung Cancer 86:195-200 (2014). Human . PubMed: 25249428
  • Terwisscha van Scheltinga AG  et al. In vivo visualization of MET tumor expression and anticalin biodistribution with the MET-specific anticalin 89Zr-PRS-110 PET tracer. J Nucl Med 55:665-71 (2014). IHC ; Human . PubMed: 24614223
  • Ito Y  et al. Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling. Am J Physiol Lung Cell Mol Physiol 307:L94-105 (2014). Human . PubMed: 24748602
  • Mitamura T  et al. Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET. Oncogenesis 2:e40 (2013). IHC-P ; Human . PubMed: 23552883
  • Nicastro HL  et al. 3,3'-Diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells. J Nutr Biochem 24:1882-8 (2013). PubMed: 23968581
  • Hagman Z  et al. The tumour suppressor miR-34c targets MET in prostate cancer cells. Br J Cancer 109:1271-8 (2013). PubMed: 23922103
  • Jacobsen F  et al. High c-MET expression is frequent but not associated with early PSA recurrence in prostate cancer. Exp Ther Med 5:102-106 (2013). IHC-P ; Human . PubMed: 23251249
  • Tsai CH  et al. Timosaponin AIII Suppresses Hepatocyte Growth Factor-Induced Invasive Activity through Sustained ERK Activation in Breast Cancer MDA-MB-231 Cells. Evid Based Complement Alternat Med 2013:421051 (2013). PubMed: 23878598
  • Saigusa S  et al. Inhibition of HGF/cMET expression prevents distant recurrence of rectal cancer after preoperative chemoradiotherapy. Int J Oncol 40:583-91 (2012). PubMed: 21922134
  • Ohe M  et al. Stromal micropapillary component as a novel unfavorable prognostic factor of lung adenocarcinoma. Diagn Pathol 7:3 (2012). IHC-P ; Human . PubMed: 22225786
  • Toiyama Y  et al. Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer. Int J Cancer 130:2912-21 (2012). PubMed: 21796631
  • Kawamura M  et al. Correlation of MACC1 and MET expression in rectal cancer after neoadjuvant chemoradiotherapy. Anticancer Res 32:1527-31 (2012). IHC-P ; Human . PubMed: 22493396
  • Sakamoto K  et al. Pleomorphic phenotypes of gastrointestinal stromal tumors at metastatic sites with or without imatinib treatment. Cancer Sci 101:1270-8 (2010). PubMed: 20180814
  • Eaton CL  et al. Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer. Prostate 70:875-82 (2010). PubMed: 20127735
  • Ke AW  et al. Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma. Hepatology 49:491-503 (2009). WB, ICC/IF ; Human . PubMed: 19065669

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