Anti-Metabotropic Glutamate Receptor 5 antibody (ab157689)

Overview

  • Product name
    Anti-Metabotropic Glutamate Receptor 5 antibody
    See all Metabotropic Glutamate Receptor 5 primary antibodies
  • Description
    Chicken polyclonal to Metabotropic Glutamate Receptor 5
  • Host species
    Chicken
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH corresponding to different regions of Metabotropic Glutamate Receptor 5 shared between the Human (NP_001137303.1) and Mouse (Q3UVX5.2) sequences.

  • Positive control
    • Adult mouse cochlear ganglion.

Properties

Applications

Our Abpromise guarantee covers the use of ab157689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.1 - 0.2 µg/ml.

Target

  • Function
    G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 3 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glutamate receptor metabotropic 5 antibody
    • GPRC1E antibody
    • Grm5 antibody
    • GRM5_HUMAN antibody
    • Metabotropic glutamate receptor 5 antibody
    • Metabotropic glutamate receptor 5 variant F antibody
    • Metabotropic glutamate receptor 5 variant G antibody
    • Metabotropic glutamate receptor 5 variant H antibody
    • mGlu5 antibody
    • mGluR5 antibody
    • PPP1R86 antibody
    • Protein phosphatase 1 regulatory subunit 86 antibody
    see all

Images

  • Immunohistochemical analysis of adult Mouse cochlear ganglion labeling Metabotropic Glutamate Receptor 5 with ab157689 at 1/200 dilution (green) and Neuron-specific class III beta-tubulin (red).

References

ab157689 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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