Anti-Metabotropic Glutamate Receptor 5 antibody, prediluted (ab27185)

Overview

  • Product name
    Anti-Metabotropic Glutamate Receptor 5 antibody, prediluted
    See all Metabotropic Glutamate Receptor 5 primary antibodies
  • Description
    Rabbit polyclonal to Metabotropic Glutamate Receptor 5, prediluted
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Rabbit, Human
  • Immunogen

    Synthetic peptide within Human Metabotropic Glutamate Receptor 5 aa 1150 to the C-terminus (C terminal). The exact sequence is proprietary.
    Database link: P41594

  • Epitope
    ab27185 reacts with an epitope located in the C terminus region of Metabotropic Glutamate Receptor 5.
  • Positive control
    • Human brain.

Properties

Applications

Our Abpromise guarantee covers the use of ab27185 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: use neat for 10 min at room temperature. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. in particular, boil tissue sections in 10mM citrate pH 6.0 for 10 min and then cool at room temperature for 20 min.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 3 family.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Glutamate receptor metabotropic 5 antibody
      • GPRC1E antibody
      • Grm5 antibody
      • GRM5_HUMAN antibody
      • Metabotropic glutamate receptor 5 antibody
      • Metabotropic glutamate receptor 5 variant F antibody
      • Metabotropic glutamate receptor 5 variant G antibody
      • Metabotropic glutamate receptor 5 variant H antibody
      • mGlu5 antibody
      • mGluR5 antibody
      • PPP1R86 antibody
      • Protein phosphatase 1 regulatory subunit 86 antibody
      see all

    Images

    • Paraffin embedded, formalin fixed human brain tissue section stained with ab27185.

    References

    ab27185 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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