Anti-MGLUR8 antibody (ab53094)
Key features and details
- Rabbit polyclonal to MGLUR8
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-MGLUR8 antibody
See all MGLUR8 primary antibodies -
Description
Rabbit polyclonal to MGLUR8 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide corresponding to Human MGLUR8.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab53094 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53094 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/300 - 1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).
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IHC-P |
Use at an assay dependent concentration.
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Notes |
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WB
1/300 - 1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa). |
IHC-P
Use at an assay dependent concentration. |
Target
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Function
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. -
Sequence similarities
Belongs to the G-protein coupled receptor 3 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2918 Human
- Entrez Gene: 14823 Mouse
- Entrez Gene: 60590 Rat
- Omim: 601116 Human
- SwissProt: O00222 Human
- SwissProt: P47743 Mouse
- SwissProt: P70579 Rat
- Unigene: 449625 Human
see all -
Alternative names
- FLJ41058 antibody
- GLUR8 antibody
- Glutamate receptor metabotropic 8 antibody
see all
Images
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All lanes : Anti-MGLUR8 antibody (ab53094) at 1/300 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract with peptide
Predicted band size: 102 kDa
Observed band size: 102 kDa -
Immunohistochemical analysis of paraffin-embedded human brain tissue in the presence (right) and absence (left) of blocking peptide, using ab53094 at 1/50 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab53094 has been referenced in 3 publications.
- Zhang C et al. Metabotropic Glutamate Receptor 8 Is Regulated by miR-33a-5p and Functions as an Oncogene in Breast Cancer. J Oncol 2021:8002087 (2021). PubMed: 34950209
- Jantas D et al. An endogenous and ectopic expression of metabotropic glutamate receptor 8 (mGluR8) inhibits proliferation and increases chemosensitivity of human neuroblastoma and glioma cells. Cancer Lett 432:1-16 (2018). PubMed: 29885518
- Kaur K et al. Integrating Molecular Subclassification of Medulloblastomas into Routine Clinical Practice: A Simplified Approach. Brain Pathol 26:334-43 (2016). PubMed: 26222673