Product nameAnti-Metabotropic Glutamate Receptor 8 antibody
See all Metabotropic Glutamate Receptor 8 primary antibodies
DescriptionRabbit polyclonal to Metabotropic Glutamate Receptor 8
Specificityab53094 detects endogenous levels of total Metabotropic Glutamate Receptor 8 protein.
Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Synthetic peptide derived from human Metabotropic Glutamate Receptor 8
- WB: Mouse brain extracts IHC-P: Human brain tissue
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab53094 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Our Abpromise guarantee covers the use of ab53094 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/300 - 1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).|
|IHC-P||Use at an assay dependent concentration.|
FunctionReceptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
Sequence similaritiesBelongs to the G-protein coupled receptor 3 family.
Cellular localizationCell membrane.
- Information by UniProt
- FLJ41058 antibody
- GLUR8 antibody
- Glutamate receptor metabotropic 8 antibody
All lanes : Anti-Metabotropic Glutamate Receptor 8 antibody (ab53094) at 1/300 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract with peptide
Predicted band size: 102 kDa
Observed band size: 102 kDa
Immunohistochemical analysis of paraffin-embedded human brain tissue in the presence (right) and absence (left) of blocking peptide, using ab53094 at 1/50 dilution.
This product has been referenced in:
- Jantas D et al. An endogenous and ectopic expression of metabotropic glutamate receptor 8 (mGluR8) inhibits proliferation and increases chemosensitivity of human neuroblastoma and glioma cells. Cancer Lett 432:1-16 (2018). Read more (PubMed: 29885518) »