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Dear technical team,
Our customer would like to purchase MRS antibody and searched ab62742, ab69237 and ab73263.
The immunogen is Native Staphyloco ccus aureus (methicill in resistant) and our customer said it is broad so,
If you have detail immunogen information, let me know.
Thank you in advance.
Asked on Jan 27 2012
Thank you for contacting us.
Regarding the immunogens of the mentioned MRSA antibodies we have the following information:
ab62742: Unfortunately, more detailed information about the specific MRSA strain used to raise the antibody is unavailable. Please note that this antibody may cross-react with other strains of Staphylococcus aureus.
ab69237: Also, more detailed information on the immunogen of this antibody is unfortunately not available. It is not known whether the antibody can distinguish MRSA from other strains.
ab73263: The protein immunogen used in development of this antibody was purified from MRSA (strain EMRSA16), but the isoform(s) of penicillin-binding protein (PBP) was not determined. Bacteria usually express several isoforms of PBP, each form having a different molecular weight. In WB, the antibody detects a protein of ˜70 kDa, but we don't know if this is PBP2a or another form of PBP. The MRSA protein in not present in methicillin-susceptible Staphylococcus aureus, thus, the antibody recognises only methicillin-RESISTANT Staphylococcus aureus and does not react with methicillin-SENSITIVE Staphylococcus aureus. Furthermore, this antibody probably will not detect intact MRSA cells as to our knowledge the MRSA protein is not detectable on surfaces of intact cells.
We aim to provide as much information as possible to customers, so I am sorry that this has not been possible on this occasion. I hope this information is nevertheless helpful to our customer. Should you have any further questions, please do not hesitate to contact us.
Answered on Jan 27 2012