Product nameAnti-Methylated Lysine antibody
See all Methylated Lysine primary antibodies
DescriptionRabbit polyclonal to Methylated Lysine
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Species independent
Methylated KLH conjugates
- WB: protein trimethylated from human melanoma cells. IHC-P: Human breast tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituents: 50% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab76118 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceMany proteins are post translationally modified. Modifications such as phosphorylation, glycosylation, ubiquitination and methylation have been shown to play an important role in the development, physiology and disease of animals and plants. Histone lysine methylation is regarded as a very stable modification with important functions in epigenetic gene control and for organizing chromatin domains.
- Dimethylysine antibody
- Methyl lysine antibody
- N epsilon dimethyl lysine antibody
Western blot analysis of protein trimethylated from human melanoma cell (MMRU) labeling Methylated Lysine with ab76118.
Left: without competitive inhibition with N-(epsilon) Tri-methyl lysine.
Right: competitive inhibition with N-(epsilon) Tri-methyl lysine (50 μg/ml).
ab76118 staining Methylated Lysine in Human Breast tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
This product has been referenced in:
- Shimazu T et al. Role of METTL20 in regulating ß-oxidation and heat production in mice under fasting or ketogenic conditions. Sci Rep 8:1179 (2018). Read more (PubMed: 29352221) »
- Yao R et al. Lysines 207 and 325 methylation of WDR5 catalyzed by SETD6 promotes breast cancer cell proliferation and migration. Oncol Rep 40:3069-3077 (2018). Read more (PubMed: 30226578) »