Key features and details
- CYP1A1 inducer. NaV channel inhibitor.
- CAS Number: 495-85-2
- Purity: > 98%
- Soluble in ethanol
- Form / State: Solid
- Source: Synthetic
Product nameMethysticin, NaV channel inhibitor
DescriptionCYP1A1 inducer. NaV channel inhibitor.
Biological descriptionCYP1A1 inducer. NaV channel inhibitor. Reversibly blocks epileptiform activity (IC50 = 10-100 μM). Shows anxiolytic, anti-ischemic, anticonvulsant and neuroprotective effects in vivo. Orally active.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Domain Families
- HLH / Leucine Zipper
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab143519 has not yet been referenced specifically in any publications.