Key features and details
- Potent, reversible proteasome inhibitor
- CAS Number: 133407-86-0
- Purity: > 95%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Product nameMG-115, proteasome inhibitor
DescriptionPotent, reversible proteasome inhibitor
Potent, reversible 20S and 26S proteasome inhibitor (Ki values are 21 and 35 nM, respectively). Inhibits chymotrypsin-like activity. Shows proapoptotic effect in vitro.
SequenceLLX (Modifications: N-terminal benzyloxycarbonyl; C-terminal aldehyde; X-3 = Nva)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142118 has been referenced in 1 publication.
- Hirakawa T et al. LSD1-LIKE1-Mediated H3K4me2 Demethylation Is Required for Homologous Recombination Repair. Plant Physiol 181:499-509 (2019). PubMed: 31366719