Anti-MGAT4B antibody (ab168485)
Key features and details
- Rabbit polyclonal to MGAT4B
- Suitable for: IP
- Reacts with: Recombinant fragment
- Isotype: IgG
Overview
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Product name
Anti-MGAT4B antibody
See all MGAT4B primary antibodies -
Description
Rabbit polyclonal to MGAT4B -
Host species
Rabbit -
Tested applications
Suitable for: IPmore details -
Species reactivity
Reacts with: Recombinant fragment
Predicted to work with: Mouse -
Immunogen
Recombinant full length protein, corresponding to amino acids 1-563 of Human MGAT4B, Isoform 3 (Gene ID: 11282, UniProt ID: Q9UQ53-3).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168485 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IP |
Use at an assay dependent concentration. The recommended starting value of ab168485 is 30-40 µl, plus 10 µl Protein a magnetic beads, for a total reaction volume of 500 µl.
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Notes |
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IP
Use at an assay dependent concentration. The recommended starting value of ab168485 is 30-40 µl, plus 10 µl Protein a magnetic beads, for a total reaction volume of 500 µl. |
Target
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Function
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis. -
Tissue specificity
Widely expressed. Strongly overexpressed in pancreatic cancer. -
Pathway
Protein modification; protein glycosylation. -
Sequence similarities
Belongs to the glycosyltransferase 54 family. -
Cellular localization
Golgi apparatus membrane. - Information by UniProt
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Database links
- Entrez Gene: 103534 Mouse
- SwissProt: Q812F8 Mouse
- Unigene: 86759 Mouse
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Alternative names
- 3-D-mannoside beta-1 antibody
- 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B antibody
- 4-N-acetylglucosaminyltransferase IVb antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab168485 has not yet been referenced specifically in any publications.