Overview

  • Product name

  • Description

    Chicken polyclonal to mGluR1
  • Host species

    Chicken
  • Tested applications

    Suitable for: IHC-FoFr, ICCmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human mGluR1 conjugated to keyhole limpet haemocyanin. Mouse mGluR1 (NP_058672.1).
    Database link: NP_000829.2

  • Positive control

    • IHC-PFA: mouse parietal cortex, adult mouse parietal cortex, e18 mouse cochlear ganglion.
  • General notes

    Do not freeze this antibody unless you want to store it for a long period of time.

     This product was previously labelled as Metabotropic Glutamate Receptor 1, Metabotropic Glutamate Receptor 1a

     

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab153669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr 1/1000 - 1/2000. Use 2% paraformaldehyde-fixed tissues.
ICC 1/1000 - 1/2000. Use 2% paraformaldehyde-fixed cells.

Target

  • Function

    Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 3 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Glutamate receptor metabotropic 1 antibody
    • glutamate receptor, metabotropic 1 antibody
    • GPRC1A antibody
    • GRM1 antibody
    • GRM1-Alpha antibody
    • GRM1_HUMAN antibody
    • GRM1A antibody
    • Metabotropic glutamate receptor 1 antibody
    • mGlu1 antibody
    • mGluR1 antibody
    • MGLUR1-Alpha antibody
    • MGLUR1A antibody
    • SCAR13 antibody
    see all

Images

  • Immunohistochemistry (PFA perfusion fixed frozen sections) of e18 mouse cochlear ganglion using ab153669 at a dilution of 1/1000 (Green). anti-Neurofilament antibody (1/500) was used as a counterstain (Red).

  • Immunohistochemistry (PFA perfusion fixed frozen sections) analysis of adult mouse parietal cortex labelling mGluR1 (red) with ab153669. Tissue was fixed with 7.5% formalin. Green - rabbit anti-GFP-expressing cells.

  • Immunohistochemistry (PFA perfusion fixed frozen sections) analysis of adult mouse parietal cortex labelling mGluR1 (red) with ab153669. Tissue was fixed with 7.5% formalin. Green - rabbit anti-GFP-expressing cells.

  • Immunohistochemistry (PFA perfusion fixed frozen sections) of e18 mouse cochlear ganglion using ab153669 at a dilution of 1/1000 (Green). anti-Neurofilament antibody (1/500) was used as a counterstain (Red).

  • Immunohistochemistry (PFA perfusion fixed frozen sections) of e18 mouse cochlear ganglion using ab153669 at a dilution of 1/1000 (Green). anti-Neurofilament antibody (1/500) was used as a counterstain (Red).

References

ab153669 has not yet been referenced specifically in any publications.

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