Overview

  • Product name

  • Description

    Rabbit polyclonal to mGluR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-FoFr, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chicken, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human mGluR1 (C terminal).

  • Positive control

    • Human brain for Immunohistochemistry.
  • General notes

     This product was previously labelled as Metabotropic Glutamate Receptor 1, Metabotropic Glutamate Receptor 1a

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.6
    Preservative: 0.1% Sodium azide
    Constituents: PBS, 1% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    This antibody is affinity purified.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration. PubMed: 17455332
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 3 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Glutamate receptor metabotropic 1 antibody
    • glutamate receptor, metabotropic 1 antibody
    • GPRC1A antibody
    • GRM1 antibody
    • GRM1-Alpha antibody
    • GRM1_HUMAN antibody
    • GRM1A antibody
    • Metabotropic glutamate receptor 1 antibody
    • mGlu1 antibody
    • mGluR1 antibody
    • MGLUR1-Alpha antibody
    • MGLUR1A antibody
    • SCAR13 antibody
    see all

Images

  • Ab27199 at a dilution of 1/50, staining mGluR1 in paraffin embedded formalin fixed human brain tissue section.

References

This product has been referenced in:

  • Higa KK  et al. Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice. Psychopharmacology (Berl) 234:1573-1586 (2017). Read more (PubMed: 28243714) »
  • Yip D  et al. A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma. Clin Cancer Res 15:3896-902 (2009). IHC-P ; Human . Read more (PubMed: 19458050) »
See all 3 Publications for this product

Customer reviews and Q&As

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Rat Tissue sections (Brain - Striatum)
Specification
Brain - Striatum

Dr. Sophie Pezet

Verified customer

Submitted Aug 18 2011

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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