Anti-mGluR1 antibody - N-terminal (ab189058)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-mGluR1 antibody - N-terminal
See all mGluR1 primary antibodies -
Description
Rabbit polyclonal to mGluR1 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Hamster, Cow, Dog, Chimpanzee, Monkey, Gorilla
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Immunogen
Synthetic peptide within Human mGluR1 (N terminal). The exact sequence is proprietary. 17 amino acid synthetic peptide from N-terminal extracellular domain of Human mGluR1.
Database link: Q13255 -
Positive control
- Human brain, neurons and glia tissue.
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General notes
This product was previously labelled as Metabotropic Glutamate Receptor 1, Metabotropic Glutamate Receptor 1a
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab189058 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 17 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. -
Sequence similarities
Belongs to the G-protein coupled receptor 3 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 463049 Chimpanzee
- Entrez Gene: 484024 Dog
- Entrez Gene: 101150458 Gorilla
- Entrez Gene: 101831018 Hamster
- Entrez Gene: 100060603 Horse
- Entrez Gene: 2911 Human
- Entrez Gene: 14816 Mouse
- Entrez Gene: 100356201 Rabbit
see all -
Alternative names
- Glutamate receptor metabotropic 1 antibody
- glutamate receptor, metabotropic 1 antibody
- GPRC1A antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mGluR1 antibody - N-terminal (ab189058)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons and glia tissue labeling mGluR1 with ab189058 at 17 µg/ml.
Protocols
References
ab189058 has not yet been referenced specifically in any publications.
