Overview

  • Product name

  • Description

    Rabbit polyclonal to MGST1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Recombinant fragment within Human MGST1. The exact sequence is proprietary.
    Database link: P10620

  • Positive control

    • WB: HeLa and HepG2 whole cell lysate. IHC: Mouse and rat liver tissue.
  • General notes

     This product was previously labelled as Microsomal Glutathione S-transferase 1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 18 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.
  • Tissue specificity

    Highly expressed in liver.
  • Sequence similarities

    Belongs to the MAPEG family.
  • Post-translational
    modifications

    Peroxynitrite induces nitration at Tyr-93 which activates the enzyme.
  • Cellular localization

    Microsome. Mitochondrion outer membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGST1 antibody
    • Glutathione S transferase 12 antibody
    • GST12 antibody
    • MGST 1 antibody
    • MGST antibody
    • MGST I antibody
    • MGST1 antibody
    • MGST1_HUMAN antibody
    • Microsomal glutathione S-transferase 1 antibody
    • Microsomal GST 1 antibody
    • Microsomal GST-1 antibody
    • Microsomal GST-I antibody
    see all

Images

  • All lanes :

    Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 2 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 18 kDa



    15% SDS-PAGE

  • Paraffin-embedded mouse liver tissue stained for MGST1 protein using ab228947 at 1/500 dilution in immunohistochemical analysis.

  • Paraffin-embedded rat liver tissue stained for MGST1 protein using ab228947 at 1/500 dilution in immunohistochemical analysis.

References

ab228947 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228947.
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