Key features and details
- Mouse monoclonal [AF6-184.108.40.206] to MHC class I (Biotin)
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2a
Product nameAnti-MHC class I antibody [AF6-220.127.116.11] (Biotin)
See all MHC class I primary antibodies
DescriptionMouse monoclonal [AF6-18.104.22.168] to MHC class I (Biotin)
SpecificityReacts with the H-2Kb MHC class I alloantigen. Reactivity to other haplotypes (e.g. d, f, j, k, p, q, r, s, u, and v) has not been observed.
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
C57BL Mouse splenocytes.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Concentration information loading...
Our Abpromise guarantee covers the use of ab93528 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceMHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
Cellular localizationCell Membrane; Type I membrane protein.
- A 28 antibody
- A 9 antibody
- Antigen presenting molecule antibody
ab93528 has not yet been referenced specifically in any publications.