Anti-MHC Class I H2 Kd antibody [SF1-1.1.1] - Low endotoxin, Azide free (ab171256)

Overview

  • Product name
    Anti-MHC Class I H2 Kd antibody [SF1-1.1.1] - Low endotoxin, Azide free
  • Description
    Mouse monoclonal [SF1-1.1.1] to MHC Class I H2 Kd - Low endotoxin, Azide free
  • Host species
    Mouse
  • Tested applications
    Suitable for: Flow Cyt, Functional Studiesmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • Mouse splenocytes.
  • General notes

    Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Constituent: PBS

    Aqueous buffer, no sodium azide.
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    SF1-1.1.1
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171256 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.125µg for 105-8 cells.

(in a final volume of 100 μl).

ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Functional Studies Use at an assay dependent concentration.

Target

  • Relevance
    MHC Class I H2 Kd is involved in the presentation of foreign antigens to the immune system. The “classical” MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant Beta2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • class I major histocompatibility antigen H 2Kd antibody
    • H 2 class I histocompatibility antigen K D alpha chain [Precursor] antibody
    • H 2K antibody
    • H2 K1 antibody
    • MHC class I H2 K b alpha 2 cell surface glycoprotein antibody
    • MHC class I heavy chain H2 K antibody
    • MHC H2 K transplantation antigen antibody
    • MHC K bm6 transplantation antigen antibody
    see all

References

ab171256 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab171256.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up