Key features and details
- Mouse monoclonal [KSK 001-02] to MHC Class II beta
- Suitable for: IHC-FoFr, Flow Cyt, IP, WB, Other
- Reacts with: Chicken
- Isotype: IgG1
Product nameAnti-MHC Class II beta antibody [KSK 001-02]
See all MHC Class II beta primary antibodies
DescriptionMouse monoclonal [KSK 001-02] to MHC Class II beta
Specificityab23488 reacts with the beta chain of chicken MHC class II, both native and denatured.
Tested applicationsSuitable for: IHC-FoFr, Flow Cyt, IP, WB, Othermore details
Species reactivityReacts with: Chicken
Tissue/ cell preparation (white blood cells from chicken plasma).
EpitopeReacts with a non-polymorphic epitope on chicken MHC class II beta chain.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride
Concentration information loading...
PurityProtein G purified
Clone numberKSK 001-02
Light chain typekappa
Our Abpromise guarantee covers the use of ab23488 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt: Use at an assay dependent dilution.
IHC-F: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 27 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceMajor Histocompatibility Class II molecules are primarily expressed on B-cells and antigen presenting cells (APCs). They are composed of two polypeptide chains. These polypeptides (alpha and beta) are about 230 and 240 amino acids long, respectively, and are glycosylated. These polypeptides fold into two separate domains; the non-polymorphic alpha chain and the polymorphic beta chain. The antigen binding region of the molecule is bounded by a beta-pleated sheet on the bottom and two alpha helices on the sides, and is capable of binding (via non-covalent interactions) a small peptide of about 10 amino acids.
Cellular localizationCell Membrane
- DPB1 antibody
- HLA-DP antibody
- HLA-DP1B antibody
ab23488 has not yet been referenced specifically in any publications.