Key features and details
- Cell-permeable, irreversible MALT1 inhibitor
- CAS Number: 1047953-91-2
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameMI 2, MALT1 inhibitor
DescriptionCell-permeable, irreversible MALT1 inhibitor
Cell-permeable, irreversible MALT1 inhibitor (IC50 = 5.8 µM). Suppresses protease function, decreases NF-κB activity and inhibits cell proliferation. Antitumor agent. Active in vitro, in vivo and ex vivo.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 50 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145047 has not yet been referenced specifically in any publications.