Overview

  • Product name

    MI 2, MALT1 inhibitor
  • Description

    Cell-permeable, irreversible MALT1 inhibitor
  • Biological description

    Cell-permeable, irreversible MALT1 inhibitor (IC50 = 5.8 µM). Suppresses protease function, decreases NF-κB activity and inhibits cell proliferation. Antitumor agent. Active in vitro, in vivo and ex vivo.
  • Purity

    > 98%
  • CAS Number

    1047953-91-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]acetamide
  • Molecular weight

    455.73
  • Molecular formula

    C19H17Cl3N4O3
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 50 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    ClCC(=O)Nc1ccc(cc1)n3nc(nc3c2ccc(Cl)c(Cl)c2)OCCOC
  • Source

    Synthetic

References

This product has been referenced in:

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab145047.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up