Anti-MIA2 antibody (ab58973)
Key features and details
- Rabbit polyclonal to MIA2
- Suitable for: Sandwich ELISA, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MIA2 antibody -
Description
Rabbit polyclonal to MIA2 -
Host species
Rabbit -
Tested applications
Suitable for: Sandwich ELISA, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Highly pure (>98%) recombinant MIA2 (human).
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Positive control
- WB: Recombinant Human MIA2.
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General notes
Although some customers have been successful in IHC we no longer batch test in this application.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab58973 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Sandwich ELISA |
Use a concentration of 0.5 - 2 µg/ml.
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WB |
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 62 kDa.
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Notes |
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Sandwich ELISA
Use a concentration of 0.5 - 2 µg/ml. |
WB
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 62 kDa. |
Target
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Function
May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. -
Tissue specificity
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. -
Sequence similarities
Belongs to the MIA/OTOR family.
Contains 1 SH3 domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 117153 Human
- Omim: 608001 Human
- SwissProt: Q96PC5 Human
- Unigene: 287694 Human
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Alternative names
- FLJ22404 antibody
- Melanoma inhibitory activity 2 antibody
- Melanoma inhibitory activity protein 2 antibody
see all
Datasheets and documents
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Datasheet download
References (3)
ab58973 has been referenced in 3 publications.
- Hei R et al. CircNRIP1 acts as a sponge of miR-1200 to suppress osteosarcoma progression via upregulation of MIA2. Am J Cancer Res 12:2833-2849 (2022). PubMed: 35812061
- Kurihara-Shimomura M et al. Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma. Int J Oncol 56:1093-1100 (2020). PubMed: 32319583
- Xu Y et al. The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene. Biochem Biophys Res Commun 416:379-84 (2011). Sandwich ELISA . PubMed: 22120627