Overview

  • Product name

    Mildronate, Fatty acid oxidation inhibitor
  • Description

    Fatty acid oxidation inhibitor
  • Biological description

    Fatty acid oxidation inhibitor. GBB hydrolase-dependent L-carnitine biosynthesis inhibitor. Competitive renal carnitine reabsorption inhibitor. γ-butyrobetaine structural analog. Shows central effects. Shows anti-ischemic and neuroprotective effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    76144-81-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Beitnere U  et al. Mildronate improves cognition and reduces amyloid-ß pathology in transgenic Alzheimer's disease mice. J Neurosci Res 92:338-46 (2014). Read more (PubMed: 24273007) »
  • Beitnere U  et al. Carnitine congener mildronate protects against stress- and haloperidol-induced impairment in memory and brain protein expression in rats. Eur J Pharmacol 745:76-83 (2014). Read more (PubMed: 25446926) »
  • Klusa V  et al. Mildronate and its neuroregulatory mechanisms: targeting the mitochondria, neuroinflammation, and protein expression. Medicina (Kaunas) 49:301-9 (2013). Read more (PubMed: 24375241) »

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