Product nameMint-1 peptide
Our Abpromise guarantee covers the use of ab4980 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat Mint 1, catalog ab3448. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
Previously labelled as APBA1.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
- Adapter protein X11 alpha
- Adapter protein X11alpha
- Amyloid beta A4 precursor protein-binding family A member 1
FunctionPutative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
Tissue specificityBrain and spinal cord.
Sequence similaritiesContains 2 PDZ (DHR) domains.
Contains 1 PID domain.
DomainComposed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
- Information by UniProt
ab4980 has not yet been referenced specifically in any publications.