Overview

  • Product name

    Anti-Mint3 antibody - N-terminal
    See all Mint3 primary antibodies
  • Description

    Rabbit polyclonal to Mint3 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Mint3 (N terminal). The exact sequence is proprietary. Conjugated to a protein carrier.
    Database link: O96018

  • Positive control

    • WB: HEK-239T, A431 and HeLa whole cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab229778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 61 kDa.

Target

  • Function

    May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.
  • Tissue specificity

    Expressed in all tissues examined with lower levels in brain and testis.
  • Sequence similarities

    Contains 2 PDZ (DHR) domains.
    Contains 1 PID domain.
  • Domain

    Composed of an N-terminal domain, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.
  • Cellular localization

    Cytoplasm > perinuclear region.
  • Information by UniProt
  • Database links

  • Alternative names

    • Adapter protein X11gamma antibody
    • amyloid beta (A4) precursor protein binding, family A, member 3 antibody
    • Amyloid beta A4 precursor protein-binding family A member 3 antibody
    • Amyloid beta precursor protein binding, family A, member 3 phosphotyrosine binding/ interacting domain (PTB) bearing protein antibody
    • APBA3 antibody
    • APBA3_HUMAN antibody
    • lin 10 antibody
    • MGC:15815 antibody
    • Mint 3 antibody
    • Mint-3 antibody
    • Neuron specific X11L2 protein antibody
    • Neuron-specific X11L2 protein antibody
    • Neuronal Munc18 1 interacting protein 3 antibody
    • Neuronal Munc18-1-interacting protein 3 antibody
    • phosphotyrosine binding/interacting domain (PTB) bearing protein antibody
    • X11 like 2 protein 2 antibody
    • X11gamma antibody
    • X11L2 antibody
    see all

Images

  • All lanes : Anti-Mint3 antibody - N-terminal (ab229778) at 1/1000 dilution

    Lane 1 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extracts
    Lane 2 : A431 (Human epidermoid carcinoma cell line) whole cell extracts
    Lane 3 : HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell extracts

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 61 kDa



    7.5% SDS-PAGE

References

ab229778 has not yet been referenced specifically in any publications.

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