Recombinant Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)
![Western blot - Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)](https://www.abcam.com/ps/products/192/ab192871/Images/ab192871-230637-anti-macrophage-inflammatory-protein-3-beta-antibody-epr70432-western-blot.jpg "Western blot - Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7043(2)] to MIP-3 beta/CCL19
- Suitable for: WB
- Reacts with: Recombinant fragment
Overview
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Product name
Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)]
See all MIP-3 beta/CCL19 primary antibodies -
Description
Rabbit monoclonal [EPR7043(2)] to MIP-3 beta/CCL19 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Recombinant fragment
Predicted to work with: Human
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Immunogen
within Human MIP-3 beta/CCL19 aa 1 to the C-terminus. The exact sequence is proprietary.
Database link: Q99731 -
Positive control
- MIP-3 beta/CCL19 recombinant protein
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General notes
This product was previously labelled as Macrophage Inflammatory Protein 3 beta
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 0.05% BSA, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR7043(2) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Related Products
Applications
Our Abpromise guarantee covers the use of ab192871 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/2000. Detects a band of approximately 11 kDa (predicted molecular weight: 11 kDa). |
Target
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Function
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. -
Tissue specificity
Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 6363 Human
- Omim: 602227 Human
- SwissProt: Q99731 Human
- Unigene: 50002 Human
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Alternative names
- Beta chemokine exodus 3 antibody
- Beta-chemokine exodus-3 antibody
- C C chemokine ligand 19 antibody
see all
Images
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Western blot - Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871) at 1/2000 dilution + MIP-3 beta/CCL19 recombinant protein at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 11 kDa
Observed band size: 11 kDa -
![Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)](https://www.abcam.com/ps/products/192/ab192871/Images/ab192871-2-benefits-of-recombinant-antibodies.png)
Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)
References (0)
ab192871 has not yet been referenced specifically in any publications.
