Recombinant Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)
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- References
- Protocols
Overview
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Product name
Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)]
See all MIP-3 beta/CCL19 primary antibodies -
Description
Rabbit monoclonal [EPR7043(2)] to MIP-3 beta/CCL19 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Recombinant fragment
Predicted to work with: Human
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Immunogen
within Human MIP-3 beta/CCL19 aa 1 to the C-terminus. The exact sequence is proprietary.
Database link: Q99731 -
Positive control
- MIP-3 beta/CCL19 recombinant protein
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General notes
This product was previously labelled as Macrophage Inflammatory Protein 3 beta
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 0.05% BSA, 50% Glycerol -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR7043(2) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Related Products
Applications
Our Abpromise guarantee covers the use of ab192871 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/2000. Detects a band of approximately 11 kDa (predicted molecular weight: 11 kDa). |
Target
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Function
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. -
Tissue specificity
Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 6363 Human
- Omim: 602227 Human
- SwissProt: Q99731 Human
- Unigene: 50002 Human
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Alternative names
- Beta chemokine exodus 3 antibody
- Beta-chemokine exodus-3 antibody
- C C chemokine ligand 19 antibody
see all
Images
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![Western blot - Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)](https://www.abcam.com/ps/products/192/ab192871/Images/ab192871-230637-anti-macrophage-inflammatory-protein-3-beta-antibody-epr70432-western-blot.jpg)
Western blot - Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871)Anti-MIP-3 beta/CCL19 antibody [EPR7043(2)] (ab192871) at 1/2000 dilution + MIP-3 beta/CCL19 recombinant protein at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 11 kDa
Observed band size: 11 kDa
Protocols
Datasheets and documents
References
ab192871 has not yet been referenced specifically in any publications.
