Anti-MIST-1 antibody [6E8/A12/C11P1] - C-terminal (ab110919)
Key features and details
- Mouse monoclonal [6E8/A12/C11P1] to MIST-1 - C-terminal
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-MIST-1 antibody [6E8/A12/C11P1] - C-terminal
See all MIST-1 primary antibodies -
Description
Mouse monoclonal [6E8/A12/C11P1] to MIST-1 - C-terminal -
Host species
Mouse -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide corresponding to Mouse MIST-1 aa 175-197 (C terminal).
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Positive control
- Mouse pancreas tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
6E8/A12/C11P1 -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab110919 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50.
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Notes |
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IHC-P
1/50. |
Target
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Function
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. -
Tissue specificity
Expressed in brain, liver, spleen and skeletal muscle. -
Sequence similarities
Contains 1 basic helix-loop-helix (bHLH) domain. -
Domain
Lacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 17341 Mouse
- SwissProt: Q9QYC3 Mouse
- Unigene: 386767 Mouse
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Alternative names
- Basic helix loop helix domain containing class B 8 antibody
- Basic helix loop helix family member a15 antibody
- BHA15_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab110919 has been referenced in 1 publication.
- Kim D et al. 3D Organoid Culture From Adult Salivary Gland Tissues as an ex vivo Modeling of Salivary Gland Morphogenesis. Front Cell Dev Biol 9:698292 (2021). PubMed: 34458260