Recombinant
RabMAb

Recombinant Anti-Mitofusin 1 antibody [EPR7960] - BSA and Azide free (ab248315)

Overview

  • Product name

    Anti-Mitofusin 1 antibody [EPR7960] - BSA and Azide free
    See all Mitofusin 1 primary antibodies
  • Description

    Rabbit monoclonal [EPR7960] to Mitofusin 1 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cyt, IP, WBmore details
    Unsuitable for: ICC/IF or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Mitofusin 1 aa 550-650. The exact sequence is proprietary.

  • General notes

    ab248315 is a PBS-only buffer format of ab129154. Please refer to ab129154 for recommended dilutions, protocols, and image data.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab248315 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 86 kDa (predicted molecular weight: 84 kDa).
  • Application notes
    Is unsuitable for ICC/IF or IHC-P.
  • Target

    • Function

      Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
    • Tissue specificity

      Ubiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers.
    • Sequence similarities

      Belongs to the mitofusin family.
    • Post-translational
      modifications

      Ubiquitinated by MARCH5.
    • Cellular localization

      Cytoplasm and Mitochondrion outer membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • Fzo homolog antibody
      • Hfzo1 antibody
      • Hfzo2 antibody
      • MFN 1 antibody
      • Mfn1 antibody
      • MFN1_HUMAN antibody
      • Mitochondrial transmembrane GTPase Fzo 1 antibody
      • Mitochondrial transmembrane GTPase FZO 2 antibody
      • Mitochondrial transmembrane GTPase FZO1B antibody
      • Mitofusin 1 antibody
      • Mitofusin-1 antibody
      • Mitofusin1 antibody
      • MS996 antibody
      • Putative transmembrane GTPase antibody
      • Transmembrane GTPase MFN1 antibody
      see all

    References

    ab248315 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab248315.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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