MitoPerOx, fluorescent mitochondria-targeted lipid peroxidation probe (ab146820)
Key features and details
- Ratiometric, fluorescent, mitochondria-targeted lipid peroxidation probe
- CAS Number: 1392820-50-6
- Purity: > 95%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
MitoPerOx, fluorescent mitochondria-targeted lipid peroxidation probe -
Description
Ratiometric, fluorescent, mitochondria-targeted lipid peroxidation probe -
Purity
> 95% -
CAS Number
1392820-50-6 -
Chemical structure
Properties
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Emission
590nm -
Chemical name
4,4-Difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-indacene-3-(propionylaminoethylentriphenylphosphonium) bromide -
Molecular weight
760.46 -
Molecular formula
C42H38BF2N3OP.Br -
Storage instructions
Store at -20°C long term. Store In the Dark. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
[Br-].F[B-]7(F)[N+]=2C(C=CC=2\C=C\C=C\c1ccccc1)=Cc6ccc(CCC(=O)NCC[P+](c3ccccc3)(c4ccccc4)c5ccccc5)n67 -
Source
Synthetic
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab146820 has been referenced in 2 publications.
- Wilcock DJ et al. Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached. Cell Rep 39:110995 (2022). PubMed: 35732120
- Shekhova E et al. Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus. Antimicrob Agents Chemother 61:N/A (2017). PubMed: 28848005