Overview

  • Product name

    Mitotane, adrenolytic and antineoplastic agent
  • Description

    Potent adrenolytic and antineoplastic agent
  • Biological description

    Potent adrenolytic and antineoplastic agent. Induces caspase-mediated apoptosis. Reduces cortisol secretion in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    53-19-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Gentilin E  et al. Mitotane reduces human and mouse ACTH-secreting pituitary cells viability and function. J Endocrinol : (2013). Read more (PubMed: 23814013) »
  • Luconi M & Mannelli M Xenograft models for preclinical drug testing: implications for adrenocortical cancer. Mol Cell Endocrinol 351:71-7 (2012). Read more (PubMed: 22056412) »
  • Kintzer PP & Peterson ME Mitotane (o,p'-DDD) treatment of 200 dogs with pituitary-dependent hyperadrenocorticism. J Vet Intern Med 5:182-90 (0). Read more (PubMed: 1656032) »

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