Key features and details
- Potent, selective and competitive CysLT1 receptor antagonist
- CAS Number: 115104-28-4
- Purity: > 97%
- Soluble in water to 25 mM, in ethanol to 10 mM and in DMSO
- Form / State: Solid
- Source: Synthetic
Product nameMK 571 sodium salt (L 660711 sodium salt), CysLT1 receptor antagonist
DescriptionPotent, selective and competitive CysLT1 receptor antagonist
Biological descriptionPotent, selective and competitive CysLT1 receptor antagonist (IC50 = 1.5 nM, LTD4). Potent MRP1 inhibitor. Shows anti-ischemic, anti-inflammatory and antinociceptive effects in vivo. Orally active.
Chemical name3-[[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoate sodium salt
Storage instructionsStore at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Solubility overviewSoluble in water to 25 mM, in ethanol to 10 mM and in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Domain Families
- HLH / Leucine Zipper
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144303 has not yet been referenced specifically in any publications.