Key features and details
- Rabbit polyclonal to MKK7 (phospho T275)
- Suitable for: WB
- Reacts with: Mouse, Human, African green monkey
- Isotype: IgG
Product nameAnti-MKK7 (phospho T275) antibody
See all MKK7 primary antibodies
DescriptionRabbit polyclonal to MKK7 (phospho T275)
ab192592 detects endogenous levels of MKK7 only when phosphorylated at threonine 275.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human, African green monkey
Predicted to work with: Rat
Synthetic peptide corresponding to Human MKK7 (phospho T275) conjugated to keyhole limpet haemocyanin.
Database link: O14733
- Extracts from COS7 and 3T3 cells.
This product was previously labelled as MEK7
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
PBS is without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab192592 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Our Abpromise guarantee covers the use of ab192592 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 47 kDa.|
FunctionStress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.
Tissue specificityUbiquitous; with highest level of expression in skeletal muscle. Isoform 3 is found at low levels in placenta, fetal liver, and skeletal muscle.
Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Contains 1 protein kinase domain.
modificationsActivated by phosphorylation on Ser/Thr.
Cellular localizationNucleus. Cytoplasm.
- Information by UniProt
- c-Jun N-terminal kinase kinase 2 antibody
- Dual specificity mitogen activated protein kinase kinase 7 antibody
- Dual specificity mitogen-activated protein kinase kinase 7 antibody
ab192592 has been referenced in 1 publication.
- Tang Y et al. Electroacupuncture Ameliorates Cognitive Impairment by Inhibiting the JNK Signaling Pathway in a Mouse Model of Alzheimer's Disease. Front Aging Neurosci 12:23 (2020). PubMed: 32116652