Overview

  • Product name

    Anti-MKK7 (phospho T275) antibody
    See all MKK7 primary antibodies
  • Description

    Rabbit polyclonal to MKK7 (phospho T275)
  • Host species

    Rabbit
  • Specificity

    ab192592 detects endogenous levels of MKK7 only when phosphorylated at threonine 275.

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human, African green monkey
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to Human MKK7 (phospho T275) conjugated to keyhole limpet haemocyanin.
    Database link: O14733

  • Positive control

    • Extracts from COS7 and 3T3 cells.
  • General notes

     This product was previously labelled as MEK7

     

Properties

Applications

Our Abpromise guarantee covers the use of ab192592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 47 kDa.

Target

  • Function

    Stress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.
  • Tissue specificity

    Ubiquitous; with highest level of expression in skeletal muscle. Isoform 3 is found at low levels in placenta, fetal liver, and skeletal muscle.
  • Sequence similarities

    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Activated by phosphorylation on Ser/Thr.
  • Cellular localization

    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • c-Jun N-terminal kinase kinase 2 antibody
    • Dual specificity mitogen activated protein kinase kinase 7 antibody
    • Dual specificity mitogen-activated protein kinase kinase 7 antibody
    • JNK activating kinase 2 antibody
    • JNK kinase 2 antibody
    • JNK-activating kinase 2 antibody
    • JNKK 2 antibody
    • Jnkk-2 antibody
    • Jnkk2 antibody
    • MAP kinase kinase 7 antibody
    • MAP2K7 antibody
    • MAPK/ERK kinase 7 antibody
    • MAPKK 7 antibody
    • MAPKK-7 antibody
    • MAPKK7 antibody
    • MEK 7 antibody
    • Mitogen Activated Protein Kinase kinase 7 antibody
    • MKK 7 antibody
    • MKK-7 antibody
    • MKK7 antibody
    • MP2K7_HUMAN antibody
    • PRKMK 7 antibody
    • PRKMK-7 antibody
    • PRKMK7 antibody
    • SAPK kinase 4 antibody
    • SAPKK-4 antibody
    • SAPKK4 antibody
    • Sek 2 antibody
    • Sek-2 antibody
    • Sek2 antibody
    • SKK4 antibody
    • stress-activated protein kinase kinase 4 antibody
    see all

Images

  • All lanes : Anti-MKK7 (phospho T275) antibody (ab192592) at 1/500 dilution

    Lane 1 : Extracts from COS7 cells with antigen-specific peptide
    Lane 2 : Extracts from COS7 cells
    Lane 3 : Extracts from 3T3 cells

    Predicted band size: 47 kDa

References

ab192592 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192592.
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