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Rabbit polyclonal to MKP-1
ab61201 detects endogenous levels of total MKP-1 protein.
Mouse, Rat, Human
Synthetic peptide corresponding to Human MKP-1 (C terminal). Immunogen in the range of aa 318-367
Database link: P28562
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride Without Mg2+ and Ca2+
Concentration information loading...
Immunogen affinity purified
ab61201 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 21771966
1/500 - 1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).
Use at an assay dependent concentration.
Dual specificity phosphatase that dephosphorylates MAP kinase ERK2 on both 'Thr-183' and 'Tyr-185'.
Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain. Contains 1 tyrosine-protein phosphatase domain.
Information by UniProt
CL 100 antibody
Dual Specificity Phosphatase 1 antibody
This product has been referenced in:
Szelenyi ER & Urso ML
Time-course analysis of injured skeletal muscle suggests a critical involvement of ERK1/2 signaling in the acute inflammatory response. Muscle Nerve 45:552-61 (2012).
Read more (PubMed: 22431089) »
et al. Role of ERK1/2 activation in microtubule stabilization and glucose transport in cardiomyocytes. Am J Physiol Endocrinol Metab 301:E836-43 (2011).
Read more (PubMed: 21771966) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"