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Rabbit polyclonal to MKP-1 (phospho S359)
Detects endogenous levels of MKP-1 only when phosphorylated at serine 359.
Predicted to work with:
Synthetic peptide corresponding to Human MKP-1 aa 318-367. This includes the phosphorylation site of Ser359.
(Peptide available as ab156312)
Human lung carcinoma tissue.
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride Without Mg2+ and Ca2+
Concentration information loading...
Immunogen affinity purified
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100.
Dual specificity phosphatase that dephosphorylates MAP kinase ERK2 on both 'Thr-183' and 'Tyr-185'.
Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain. Contains 1 tyrosine-protein phosphatase domain.
Information by UniProt
CL 100 antibody
Dual Specificity Phosphatase 1 antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MKP-1 (phospho S359) antibody (ab63548)
at 1/50-1/100 dilution staining human lung carcinoma tissue, without (left) and with (right) immunizing peptide; paraffin embedded.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"