Key features and details
- Rabbit polyclonal to MKP-1 (phospho S359)
- Suitable for: IHC-P, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MKP-1 (phospho S359) antibody
See all MKP-1 primary antibodies
DescriptionRabbit polyclonal to MKP-1 (phospho S359)
SpecificityDetects endogenous levels of MKP-1 only when phosphorylated at serine 359.
Tested applicationsSuitable for: IHC-P, ELISAmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide corresponding to Human MKP-1 aa 318-367. This includes the phosphorylation site of Ser359.
(Peptide available as
- Human lung carcinoma tissue.
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We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Our Abpromise guarantee covers the use of ab63548 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
FunctionDual specificity phosphatase that dephosphorylates MAP kinase ERK2 on both 'Thr-183' and 'Tyr-185'.
Tissue specificityExpressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain.
Contains 1 tyrosine-protein phosphatase domain.
- Information by UniProt
- CL 100 antibody
- CL100 antibody
- Dual Specificity Phosphatase 1 antibody
ab36548 at 1/50-1/100 dilution staining human lung carcinoma tissue, without (left) and with (right) immunizing peptide; paraffin embedded.
ab63548 has not yet been referenced specifically in any publications.