Overview

  • Product name
  • Description
    Rabbit polyclonal to MKRN3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human MKRN3 aa 167-197 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q13064

  • Positive control
    • MDA-MB435 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab174878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.

Target

  • Function
    E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
  • Tissue specificity
    Ubiquitous.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Contains 3 C3H1-type zinc fingers.
    Contains 1 RING-type zinc finger.
  • Information by UniProt
  • Database links
  • Alternative names
    • D15S9 antibody
    • Makorin ring finger protein 3 antibody
    • Mkrn3 antibody
    • MKRN3_HUMAN antibody
    • Probable E3 ubiquitin-protein ligase makorin-3 antibody
    • RING finger protein 63 antibody
    • RNF63 antibody
    • ZFP127 antibody
    • Zinc finger protein 127 antibody
    • ZNF127 antibody
    see all

Images

  • Anti-MKRN3 antibody (ab174878) at 1/100 dilution + MDA-MB435 cell line lysates at 15 µg

    Predicted band size: 56 kDa

References

This product has been referenced in:
  • Liu H  et al. Mkrn3 functions as a novel ubiquitin E3 ligase to inhibit Nptx1 during puberty initiation. Oncotarget 8:85102-85109 (2017). Read more (PubMed: 29156706) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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