Key features and details
- Rabbit polyclonal to MKS1
- Suitable for: IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-MKS1 antibody
DescriptionRabbit polyclonal to MKS1
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
- IHC-P: Human cerebral cortex, colon, fallopian tube and kidney tissues. WB: RT4 and NBT-II cell lysates.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab150807 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 65 kDa.|
FunctionComponent of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.
Involvement in diseaseMeckel syndrome 1
Bardet-Biedl syndrome 13
Sequence similaritiesContains 1 B9 domain.
Cellular localizationCytoplasm > cytoskeleton > cilium basal body. Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
- Information by UniProt
- B8d3 antibody
- BBS13 antibody
- Dysencephalia splanchnocystica antibody
All lanes : Anti-MKS1 antibody (ab150807) at 1/200 dilution
Lane 1 : NIH-3T3 (Mouse embryonic fibroblast cells) cell lysate
Lane 2 : NBT-II (Rat Wistar bladder tumour cells) cell lysate
Predicted band size: 65 kDa
Immunohistochemical analysis of human kidney tissue labeling MKS1 with ab150807 at 1/200 dilution.
Immunohistochemical analysis of human fallopian tube tissue labeling MKS1 with ab150807 at 1/200 dilution.
Immunohistochemical analysis of human colon tissue labeling MKS1 with ab150807 at 1/200 dilution.
Immunohistochemical analysis of human cerebral cortex tissue labeling MKS1 with ab150807 at 1/200 dilution.
Anti-MKS1 antibody (ab150807) at 1/200 dilution + RT4 cell lysate
Predicted band size: 65 kDa
ab150807 has not yet been referenced specifically in any publications.