Overview

  • Product name

    ML-324, JMJD2 inhibitor
  • Description

    Potent, cell-permeable JMJD2 inhibitor
  • Biological description

    Potent, cell-permeable JMJD2 inhibitor (IC50 = 920 nM). Shows antiviral effects (IC50 = 10 μM), HSV-1 immediate early gene expression). Reversibly blocks human cytomegalovirus infection in vivo.
  • CAS Number

    1222800-79-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[3-(Dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide
  • Molecular weight

    349.43
  • Molecular formula

    C21H23N3O2
  • PubChem identifier

    44143209
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 10 mM and in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)CCCNC(=O)C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)O
  • Source

    Synthetic

  • Research areas

References

ab146175 has not yet been referenced specifically in any publications.

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