Overview

  • Product name

    ML-9, protein kinase inhibitor
  • Description

    Broad spectrum ATP-competitive protein kinase inhibitor. Ca2+ channel blocker.
  • Biological description

    Broad spectrum ATP-competitive protein kinase inhibitor (Ki values are 32, 4, and 54 μM for PKA, MLCK, and PKC respectively). Ca2+ channel blocker. Shows vasorelaxant effects in vivo.
  • Purity

    > 98%
  • CAS Number

    105637-50-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Nafiu AB & Rahman MT Anti-inflammatory and antioxidant properties of unripe papaya extract in an excision wound model. Pharm Biol :1-10 (2014). Read more (PubMed: 25431122) »
  • Ito S  et al. ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealis. Eur J Pharmacol 486:325-33 (2004). Read more (PubMed: 14985055) »
  • Isemura M  et al. Myosin light chain kinase inhibitors ML-7 and ML-9 inhibit mouse lung carcinoma cell attachment to the fibronectin substratum. Cell Biol Int Rep 15:965-72 (1991). Read more (PubMed: 1773444) »

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