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ab196436 has been referenced in 40 publications.

  • Yuan Z  et al. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation. Toxicology 414:45-56 (2019). PubMed: 30633930
  • Frank D  et al. Activated MLKL attenuates autophagy following its translocation to intracellular membranes. J Cell Sci 132:N/A (2019). PubMed: 30709919
  • Dziedzic SA  et al. ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol 20:58-68 (2018). PubMed: 29203883
  • Zhu P  et al. Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway. Redox Biol 16:157-168 (2018). PubMed: 29502045
  • Zelic M  et al. RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome. J Clin Invest 128:2064-2075 (2018). PubMed: 29664014
  • Cao M  et al. c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities. Cell Death Dis 9:1140 (2018). PubMed: 30442927
  • Liang S  et al. Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1ß Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes. Front Pharmacol 9:1378 (2018). PubMed: 30542285
  • Eleftheriadis T  et al. Cell Death Patterns Due to Warm Ischemia or Reperfusion in Renal Tubular Epithelial Cells Originating from Human, Mouse, or the Native Hibernator Hamster. Biology (Basel) 7:N/A (2018). PubMed: 30445750
  • Guo H  et al. Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1. Cell Death Dis 9:816 (2018). PubMed: 30050136
  • Heger K  et al. OTULIN limits cell death and inflammation by deubiquitinating LUBAC. Nature 559:120-124 (2018). PubMed: 29950720
  • Liss KHH  et al. The impact of diet-induced hepatic steatosis in a murine model of hepatic ischemia/reperfusion injury. Liver Transpl 24:908-921 (2018). PubMed: 29729104
  • Zhou H  et al. Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury. J Pineal Res N/A:e12503 (2018). PubMed: 29770487
  • Imamura M  et al. RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase. JCI Insight 3:N/A (2018). PubMed: 29415885
  • Armaka M  et al. The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts. Nat Commun 9:618 (2018). PubMed: 29434332
  • von Mässenhausen A  et al. Phenytoin inhibits necroptosis. Cell Death Dis 9:359 (2018). PubMed: 29500402
  • Fuchslocher Chico J  et al. The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis. Oncotarget 9:12941-12958 (2018). PubMed: 29560122
  • Huang G  et al. Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p. Toxicology 406-407:33-43 (2018). PubMed: 29860048
  • González-Juarbe N  et al. Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. Cell Death Differ 24:917-928 (2017). WB, IHC ; Mouse . PubMed: 28387756
  • Lafont E  et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J 36:1147-1166 (2017). WB ; Human . PubMed: 28258062
  • Zargarian S  et al. Phosphatidylserine externalization, "necroptotic bodies" release, and phagocytosis during necroptosis. PLoS Biol 15:e2002711 (2017). WB ; Mouse . PubMed: 28650960
  • Berger AK  et al. Viral RNA at Two Stages of Reovirus Infection Is Required for the Induction of Necroptosis. J Virol 91:N/A (2017). Mouse . PubMed: 28077640
  • Daley-Bauer LP  et al. Mouse cytomegalovirus M36 and M45 death suppressors cooperate to prevent inflammation resulting from antiviral programmed cell death pathways. Proc Natl Acad Sci U S A 114:E2786-E2795 (2017). PubMed: 28292903
  • Hartmann BM  et al. Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death. Nat Commun 8:1931 (2017). PubMed: 29203926
  • Yang M  et al. Neuroprotective Effect of ß-Caryophyllene on Cerebral Ischemia-Reperfusion Injury via Regulation of Necroptotic Neuronal Death and Inflammation:In Vivoandin Vitro. Front Neurosci 11:583 (2017). PubMed: 29123466
  • Li D  et al. RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. Elife 6:N/A (2017). PubMed: 28807105
  • Ishii T  et al. CETSA quantitatively verifies in vivo target engagement of novel RIPK1 inhibitors in various biospecimens. Sci Rep 7:13000 (2017). PubMed: 29026104
  • Gong YN  et al. ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences. Cell 169:286-300.e16 (2017). PubMed: 28388412
  • Yoon S  et al. MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity 47:51-65.e7 (2017). PubMed: 28666573
  • Gong YN  et al. Biological events and molecular signaling following MLKL activation during necroptosis. Cell Cycle 16:1748-1760 (2017). PubMed: 28854080
  • Hos NJ  et al. Type I interferon enhances necroptosis of Salmonella Typhimurium-infected macrophages by impairing antioxidative stress responses. J Cell Biol 216:4107-4121 (2017). PubMed: 29055012
  • Martin-Sanchez D  et al. Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid-Induced AKI. J Am Soc Nephrol 28:218-229 (2017). PubMed: 27352622
  • Imagawa Y  et al. Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse. Nat Commun 7:13391 (2016). PubMed: 27811852
  • Li Z  et al. Tissue damage negatively regulates LPS-induced macrophage necroptosis. Cell Death Differ 23:1428-47 (2016). PubMed: 26943325
  • McCullough RL  et al. Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol-induced liver injury in mice. Mol Immunol 75:122-32 (2016). PubMed: 27280845
  • Aaes TL  et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep 15:274-87 (2016). WB ; Mouse . PubMed: 27050509
  • Afonso MB  et al. Activation of necroptosis in human and experimental cholestasis. Cell Death Dis 7:e2390 (2016). WB . PubMed: 27685634
  • Cai Z  et al. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration. Cell Res N/A:N/A (2016). WB . PubMed: 27444869
  • Pescatore A  et al. NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II. Cell Death Dis 7:e2346 (2016). PubMed: 27560715
  • Gautheron J  et al. The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance. Nat Commun 7:11869 (2016). WB . PubMed: 27323669
  • Wagner SA  et al. SPATA2 links CYLD to the TNF-a receptor signaling complex and modulates the receptor signaling outcomes. EMBO J 35:1868-84 (2016). PubMed: 27307491

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