Overview

  • Product name

    MM1-43, membrane selective dye
  • Description

    Membrane selective dye
  • Biological description

    Membrane selective dye. Reversibly binds to the outer leaflet of surface membranes without permeating. Internalizes into vesicles during endocytosis. Dissociates from the membrane during exocytosis.

    Also available in simple stock solutions (ab146741) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity

    > 99%
  • CAS Number

    149838-22-2
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    510nm
  • Emission

    510nm
  • Chemical name

    4-[2-[4-(Dibutylamino)phenyl]ethenyl]-1-[3-(triethylammonio)propyl]pyridinium dibromide
  • Molecular weight

    611.55
  • Molecular formula

    C30H49Br2N3
  • PubChem identifier

    6508724
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCN(CCCC)C1=CC=C(C=C1)C=CC2=CC=[N+](C=C2)CCC[N+](CC)(CC)CC.[Br-].[Br-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Wróbel A  et al. Monitoring of membrane phospholipid scrambling in human erythrocytes and K562 cells with FM1-43 - a comparison with annexin V-FITC. Cell Mol Biol Lett : (2014). Read more (PubMed: 24764144) »
  • Amaral E  et al. Using the fluorescent styryl dye FM1-43 to visualize synaptic vesicles exocytosis and endocytosis in motor nerve terminals. Methods Mol Biol 689:137-48 (2011). Read more (PubMed: 21153790) »
  • Bolte S  et al. FM-dyes as experimental probes for dissecting vesicle trafficking in living plant cells. J Microsc 214:159-73 (2004). Read more (PubMed: 15102063) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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