For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to MMAB
Predicted to work with:
Recombinant fragment, corresponding to a region within amino acids 19-250 of Human MMAB (UniProt ID: Q96EY8).
HepG2 whole cell lysate; Human hepatoma tissue
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 78% PBS, 20% Glycerol, 1% BSA
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 27 kDa.
1/100 - 1/1000.
Expressed in liver and skeletal muscle.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.
Involvement in disease
Defects in MMAB are the cause of methylmalonic aciduria type cblB (MMAB) [MIM:251110]; also known as methylmalonic aciduria type B or vitamin B12-responsive methylmalonicaciduria of cblB complementation type. MMAB is a disorder of methylmalonate and cobalamin metabolism due to defective synthesis of adenosylcobalamin. Inheritance is autosomal recessive.
Belongs to the Cob(I)alamin adenosyltransferase family.
Information by UniProt
aquocob(I)alamin vitamin B12s adenosyltransferase antibody
ATP:cob(I)alamin adenosyltransferase antibody
ATP:corrinoid adenosyltransferase antibody
Western blot - Anti-MMAB antibody (ab154156)
Anti-MMAB antibody (ab154156) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 27 kDa 12% SDS PAGE
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMAB antibody (ab154156)
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue labeling MMAB with ab154156 at 1/500 dilution.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"