Key features and details
- Goat polyclonal to mMCP-4
- Suitable for: IHC-P
- Isotype: IgG
Product nameAnti-mMCP-4 antibody
DescriptionGoat polyclonal to mMCP-4
Tested applicationsSuitable for: IHC-Pmore details
Predicted to work with: Mouse
Previously labelled as MCPT4.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab92368 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab92368 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
FunctionHas chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-
-Ile-5' bond of angiotensin I and the 'Phe-20-
-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-
-His-9' bond of angiotensin I and the 'Phe-4-
-Ala-5' and 'Tyr-10-
-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing.
Tissue specificitySubmucosal mast cells. In femoral muscle, detected in myocytes but not in mast cells.
Sequence similaritiesBelongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain.
- Information by UniProt
- Mast cell protease 4 antibody
- Mcp 4 antibody
- Mcpt4 antibody
ab92368 has been referenced in 1 publication.
- Rowbotham SP et al. H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression. Nat Commun 9:4559 (2018). PubMed: 30455465