Key features and details
- Rabbit polyclonal to MMP23
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-MMP23 antibody
See all MMP23 primary antibodies
DescriptionRabbit polyclonal to MMP23
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide derived from human MMP23.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab53148 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).|
FunctionProtease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
Tissue specificityPredominantly expressed in ovary, testis and prostate.
Sequence similaritiesBelongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
DomainThe toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
Proteolytic cleavage might yield an active form.
Cellular localizationEndoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
- Information by UniProt
- Femalysin antibody
- Matrix metallopeptidase 21 antibody
- Matrix metallopeptidase 23A (pseudogene) antibody
ab53148 has been referenced in 1 publication.
- Miller JP et al. Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease. Neuron 67:199-212 (2010). WB ; Human . PubMed: 20670829