Key features and details
- Rabbit monoclonal [EP1341(2)] to MMP28
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-MMP28 antibody [EP1341(2)]
DescriptionRabbit monoclonal [EP1341(2)] to MMP28
Tested applicationsSuitable for: WBmore details
Unsuitable for: ICC/IF,IHC-P or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human MMP28 aa 450 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
Database link: Q9H239
- Human placenta, human testis lysate, recombinant protein fragment
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab175937 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Detects a band of approximately 62 kDa (predicted molecular weight: 59 kDa).|
FunctionCan degrade casein. Could play a role in tissues homeostasis and repair.
Tissue specificityExpressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytesis. Widely expressed in several carcinomas as well. Is up-regulated in response to injury in the skin.
Sequence similaritiesBelongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.
DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
modificationsThe precursor is cleaved by a furin endopeptidase.
Cellular localizationSecreted > extracellular space > extracellular matrix.
- Information by UniProt
- Epilysin antibody
- Matrix metalloproteinase 28 antibody
- Matrix metalloproteinase-28 antibody
Anti-MMP28 antibody [EP1341(2)] (ab175937) at 1/1000 dilution + MMP-28 recombinant protein fragment at 0.01 µg
Predicted band size: 59 kDa
All lanes : Anti-MMP28 antibody [EP1341(2)] (ab175937) at 1/1000 dilution
Lane 1 : Human placenta lysate
Lane 2 : Human testis lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 59 kDa
ab175937 has been referenced in 1 publication.
- Su C et al. MiR-21 improves invasion and migration of drug-resistant lung adenocarcinoma cancer cell and transformation of EMT through targeting HBP1. Cancer Med 7:2485-2503 (2018). WB ; Human . PubMed: 29663730