MMP3 Inhibitor Screening Assay Kit (Fluorometric) (ab139440)

Overview

  • Product name
    MMP3 Inhibitor Screening Assay Kit (Fluorometric)
    See all MMP3 kits
  • Assay type
    Enzyme activity
  • Product overview

    Abcam MMP3 Inhibitor Screening Assay Kit (Fluorometric) (ab139440)  is a complete assay system designed to screen MMP3 inhibitors using a quenched fluorogenic peptide: MMP Fluorogenic Substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 [Mca=(7-methoxycoumarin-4-yl)-acetyl; Dpa=N-3-(2,4-dinitrophenyl)-L-α-β-diaminopropionyl]. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP3, a potential therapeutic target. The compound NNGH is also included as a prototypic control inhibitor.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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