Overview

  • Product name

  • Description

    Rabbit polyclonal to MMP7
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide aa 165-210 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    DSFPFD GPGNTLGHAF APGPGLGGDA HFDKDEYWTD GEDAGVNFLF


    Database link: Q10738

  • Positive control

    • WB: Mouse uterus lysate. IHC-P: Human colon carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab216631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/100 - 1/1000. Predicted molecular weight: 29 kDa.

Target

  • Function

    Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • Sequence similarities

    Belongs to the peptidase M10A family.
  • Domain

    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • Matrilysin antibody
    • Matrin antibody
    • Matrix Metalloproteinase 7 antibody
    • Matrix metalloproteinase-7 antibody
    • MMP 7 antibody
    • MMP-7 antibody
    • MMP7 antibody
    • MMP7_HUMAN antibody
    • MPSL1 antibody
    • PUMP 1 antibody
    • Pump 1 protease antibody
    • Pump-1 protease antibody
    • PUMP1 antibody
    • Uterine matrilysin antibody
    • Uterine metalloproteinase antibody
    see all

Images

  • Anti-MMP7 antibody (ab216631) at 1/300 dilution + mouse uterus lysate

    Predicted band size: 29 kDa

  • Immunohistochemical analysis of formalin-fixed and paraffin embedded human colon carcinoma tissue labeling MMP7 using ab216631 at 1/200, followed by secondary detection and DAB staining.

  • Immunohistochemical analysis of formalin-fixed and paraffin embedded human colon carcinoma tissue labeling MMP7 using ab216631 at 1/200, followed by secondary detection and DAB staining.

References

ab216631 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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