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Rabbit polyclonal to MMP8
Recombinant fragment corresponding to a region within amino acids 96-467 of Human MMP8 (P22894).
HCT116 whole cell lysate, A431 cells, Human hepatoma tissue
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 78% PBS, 20% Glycerol, 1% BSA
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/5000 - 1/20000. Predicted molecular weight: 53 kDa.
1/100 - 1/1000.
1/100 - 1/1000.
Can degrade fibrillar type I, II, and III collagens.
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Cytoplasmic granule. Secreted > extracellular space > extracellular matrix. Stored in intracellular granules.
Information by UniProt
CLG 1 antibody
Collagenase 1 antibody
Western blot - Anti-MMP8 antibody (ab154507)
Anti-MMP8 antibody (ab154507) at 1/10000 dilution + HCT116 whole cell
lysate at 30 µg Predicted band size: 53 kDa 7.5% SDS PAGE
Immunocytochemistry/ Immunofluorescence - Anti-MMP8 antibody (ab154507)
Immunofluorescent analysis of methanol-fixed A431 cells labeling MMP8 with ab154507 at 1/500 dilution. Image at the bottom costained with Hoechst 33342.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMP8 antibody (ab154507)
Immunohistochemical analysis of paraffin embedded Human hepatoma tissue labeling MMP8 with ab154507 antibody at 1/500.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"