Key features and details
- Rabbit polyclonal to MMS2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-MMS2 antibody
See all MMS2 primary antibodies
DescriptionRabbit polyclonal to MMS2
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Chicken, Cow, Dog, Pig, Xenopus laevis, Zebrafish, Xenopus tropicalis
Recombinant fragment corresponding to a region within amino acids 1-145 of Human MMS2 (Q15819).
- HL-60 and BCL-1 whole cell lysate. HBL435 xenograft tissue. C2C12 xenograft tissue.
General notesKeep as concentrated solution.
This product was previously labelled as Ube2v2, MMS2
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
- Cell Biology
- Proteolysis / Ubiquitin
- Proteasome / Ubiquitin
- Ubiquitin E3 Enzymes
- RING Finger E3 Ligase
Our Abpromise guarantee covers the use of ab155007 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 16 kDa.|
|IHC-P||1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionHas no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Tissue specificityDetected in placenta, colon, liver and skin. Detected at very low levels in most tissues.
Sequence similaritiesBelongs to the ubiquitin-conjugating enzyme family.
- Information by UniProt
- 1 alpha 25 dihydroxyvitamin D3 inducible antibody
- DDVit 1 antibody
- DDVIT1 antibody
Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, labelling MMS2 with ab155007 at 1/500 dilution.
Anti-MMS2 antibody (ab155007) at 1/1000 dilution + HL-60 whole cell lysate at 30 µg
Predicted band size: 16 kDa
15% SDS PAGE
Anti-MMS2 antibody (ab155007) at 1/1000 dilution + BCL-1 whole cell lysate at 30 µg
Predicted band size: 16 kDa
15% SDS PAGE
Immunohistochemical analysis of paraffin-embedded C2C12 xenograft, labelling MMS2 with ab155007 at 1/500 dilution.
ab155007 has not yet been referenced specifically in any publications.