Anti-MMS2 antibody (ab195589)

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Key features and details

  • Rabbit polyclonal to MMS2
  • Suitable for: WB
  • Reacts with: Mouse, Rat, Human
  • Isotype: IgG

Overview

  • Product name

    Anti-MMS2 antibody
    See all MMS2 primary antibodies

  • Description

    Rabbit polyclonal to MMS2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide within Human MMS2 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q15819

  • General notes

     This product was previously labelled as Ube2v2, MMS2

     

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Applications

Our Abpromise guarantee covers the use of ab195589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/1000. Predicted molecular weight: 16 kDa.

Target

  • Function

    Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

  • Tissue specificity

    Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues.

  • Sequence similarities

    Belongs to the ubiquitin-conjugating enzyme family.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • 1 alpha 25 dihydroxyvitamin D3 inducible antibody
    • DDVit 1 antibody
    • DDVIT1 antibody
    • EDAF-1 antibody
    • EDAF1 antibody
    • EDPF-1 antibody
    • EDPF1 antibody
    • Enterocyte differentiation associated factor EDAF 1 antibody
    • Enterocyte differentiation promoting factor antibody
    • Enterocyte differentiation-associated factor 1 antibody
    • Enterocyte differentiation-promoting factor 1 antibody
    • Methyl methanesulfonate sensitive 2 antibody
    • MMS 2 antibody
    • MMS2 antibody
    • MMS2 homolog antibody
    • UB2V2_HUMAN antibody
    • UBE2V 2 antibody
    • UBE2V2 antibody
    • Ubiquitin conjugating enzyme E2 variant 2 antibody
    • Ubiquitin conjugating enzyme E2v2 antibody
    • Ubiquitin-conjugating enzyme E2 variant 2 antibody
    • UEV 2 antibody
    • UEV2 antibody
    • Vitamin D3 inducible protein antibody
    • Vitamin D3-inducible protein antibody
    see all

Images

  • Western blot - Anti-MMS2 antibody (ab195589)
    Western blot - Anti-MMS2 antibody (ab195589)
    All lanes : Anti-MMS2 antibody (ab195589) at 1/250 dilution

    Lane 1 : HeLa lysate
    Lane 2 : Human Fetal brain lysate

    Predicted band size: 16 kDa

References (0)

Publishing research using ab195589? Please let us know so that we can cite the reference in this datasheet.

ab195589 has not yet been referenced specifically in any publications.

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