Product nameAnti-MMS2 antibody
See all MMS2 primary antibodies
DescriptionGoat polyclonal to MMS2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- Human Brain lysate.
General notesPrincipal Names – UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; MMS2; UEV2; EDPF1; UEV-2; DDVIT1; EDAF-1; EDPF-1; DDVit-1; 1 alpha,25-dihydroxyvitamin D3-inducible; enterocyte differentiation promoting factor; methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of Official Gene Symbol - UBE2V2. GenBank Accession Number – NP_003341. LocusLink ID - 7336 (human); 70620 (mouse). Gene Ontology terms - cell proliferation; polyubiquitination; regulation of DNA repair; regulation of cell cycle; ubiquitin conjugating enzyme.
This product was previously labelled as Ube2v2, MMS2
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.05% Tris, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Cell Biology
- Proteolysis / Ubiquitin
- Proteasome / Ubiquitin
- Ubiquitin E3 Enzymes
- RING Finger E3 Ligase
Our Abpromise guarantee covers the use of ab2513 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.2 - 1 µg/ml.
Approx 20kDa band seen in Human Brain lysate.
FunctionHas no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Tissue specificityDetected in placenta, colon, liver and skin. Detected at very low levels in most tissues.
Sequence similaritiesBelongs to the ubiquitin-conjugating enzyme family.
- Information by UniProt
- 1 alpha 25 dihydroxyvitamin D3 inducible antibody
- DDVit 1 antibody
- DDVIT1 antibody
ab2513 has not yet been referenced specifically in any publications.